FCAR CLIA Kit for Human(Homo sapiens) | EIAab.comFCAR CLIA Kit for Human(Homo sapiens)

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FCAR (Gene name),

Immunoglobulin alpha Fc receptor (Protein name ), FCAR_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FCAR(CD89);

Protein name:

Immunoglobulin alpha Fc receptor(IgA Fc receptor);

Alternative:

CD:

CD89;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2.

Function:

Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.

Subcellular Location:

Isoform B-delta-S2 Secreted

Protein Attributes:

Sequence length:

287

Sequence:

50:

100:

150:

200:

250:

287:

SHTALNKEAS | ADVAEPSWSQ | QMCQPGLTFA | RTPSVCK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P24071

UniGene:

Hs.659872

String:

P24071

MIM:

147045

KEGG:

hsa:2204

Uniprot:

P24071

FOR

ELISA Kit for Human IgA Fc receptor

Cat.:

E1583h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human IgA Fc receptor

Cat.:

U1583h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human IgA Fc receptor

Cat.:

P1583Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human IgA Fc receptor

Protein for Human IgA Fc receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Expression cloning of a human Fc receptor for IgA."
Maliszewski C.R. , March C.J. , Schoenborn M.A. , Gimpel S. , Shen L.
J. Exp. Med.172:1665-1672(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A.1)
2.

"Structure of the gene for the human myeloid IgA Fc receptor (CD89)."
de Wit T.P.M. , Morton H.C. , Capel P.J.A. , van de Winkel J.G.J.
J. Immunol.155:1203-1209(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM A.1)
tissue: Bone marrow.
3.

"Identification of Fc alpha receptor (CD89) isoforms generated by alternative splicing that are differentially expressed between blood monocytes and alveolar macrophages."
Patry C. , Sibille Y. , Lehuen A. , Monteiro R.C.
J. Immunol.156:4442-4448(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A.2 AND A.3);TISSUE SPECIFICITY
tissue: Alveolar macrophage.
tissue: Monocyte.
4.

van Dijk T.B. , Morton H.C. , Caldenhoven E. , Bracke M. , Raaijmakers J.A.M. , Lammers J.W.J. , Koenderman L. , Groot R.P.
Submitted (1996-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORMS B AND B-DELTA-S2)
5.

"Alternative splicing of the human IgA Fc receptor CD89 in neutrophils and eosinophils."
Pleass R.J. , Andrews P.D. , Kerr M.A. , Woof J.M.
Biochem. J.318:771-777(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A.3);TISSUE SPECIFICITY
6.

"IgA nephropathy-specific expression of the IgA Fc receptors (CD89) on blood phagocytic cells."
Toyabe S. , Kuwano Y. , Takeda K. , Uchiyama M. , Abo T.
Clin. Exp. Immunol.110:226-232(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A.2; A.3; L10; U02; U09; U10; U11 AND U13)
7.

"Episodes of natural selection shaped the interactions of IgA-Fc with FcalphaRI and bacterial decoy proteins."
Abi-Rached L. , Dorighi K. , Norman P.J. , Yawata M. , Parham P.
J. Immunol.178:7943-7954(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A.1);VARIANTS ASN-113 AND GLY-269
8.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A.1)
tissue: Blood.
10.

"Association of IgA-Fc receptors (Fc alpha R) with Fc epsilon RI gamma 2 subunits in U937 cells. Aggregation induces the tyrosine phosphorylation of gamma 2."
Pfefferkorn L.C. , Yeaman G.R.
J. Immunol.153:3228-3236(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
11.

"An unappreciated role for RNA surveillance."
Hillman R.T. , Green R.E. , Brenner S.E.
Genome Biol.5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S)
12.

"Crystal structure of the ectodomain of human FcalphaRI."
Ding Y. , Xu G. , Yang M. , Yao M. , Gao G.F. , Wang L. , Zhang W. , Rao Z.
J. Biol. Chem.278:27966-27970(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 21-229;DISULFIDE BONDS
13.

"Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc."
Herr A.B. , Ballister E.R. , Bjorkman P.J.
Nature423:614-620(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 22-216 IN COMPLEX WITH IMMUNOGLOBULIN ALPHA;FUNCTION;DISULFIDE BONDS;GLYCOSYLATION AT ASN-141 AND ASN-177

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